Best Supplement Manufacturers in the USA: How to Find the Right Partner
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The U.S. supplement industry is projected to surpass $56 billion by 2027, driven by rising consumer demand for health-focused products and the growing popularity of online shopping.
For emerging ecommerce businesses, partnering with manufacturers can be a game-changer, offering access to high-quality formulations, faster production timelines, and lower overhead costs compared to in-house production.
In this guide, we’ll explore how to identify the USA's best supplement manufacturers, along with practical tips to ensure your chosen partner can grow and scale with your brand.
9 Top Supplement Manufacturers in USA: Leading Partners for Growing E-commerce Brands
Looking for the USA's top supplement manufacturers to help you create high-quality products and scale your business?
Below is a selection of top-performing companies that have built strong reputations for quality, reliability, and industry expertise.
Gemini Pharmaceuticals
Gemini Pharmaceuticals has a rich history in manufacturing custom supplements. Their decades of experience allow them to provide products developed and packaged to meet strict quality standards and deliver strong customer satisfaction.
- Revenue: $100 – 249.9 million
- Founded: 1982 (40+ years in the industry)
- Location: Commack, NY, USA
- Certifications: GMP-certified, FDA-registered facility
- Specialties: Custom formulation & contract manufacturing for vitamins, minerals, and nutraceuticals
- Production Capacity: Scalable operations to handle small to large volume orders
- Compliance: Regular third-party audits and strict quality control protocols
They’re especially valued for their ability to guide brands through complex compliance requirements, making them a reliable partner for both established companies and newcomers to the supplement industry.
Supplement Manufacturing Partner Inc.
Supplement Manufacturing Partner Inc. has rapidly emerged as a leader in the supplement manufacturing industry since 2019.
- Revenue: Not publicly disclosed
- Founded: 2019
- Location: Edgewood/Brentwood, NY, USA
- Certifications: cGMP-compliant, FDA-registered facility
- Specialties: Contract manufacturing/private label across capsules, tablets, powders, gummies; formulation, packaging
- Production Capacity: Approximately 277,000 sq ft across GMP/FDA-registered facilities
- Compliance: Operates under FDA cGMP 21 CFR 111
They specialize in a wide array of standard and custom products, ensuring quality and innovation in every batch. Their speed-to-market capabilities and in-house design team make them a go-to choice for ecommerce brands wanting to launch products quickly without sacrificing quality.
Life Solutions Contract Manufacturing
Life Solutions offers a comprehensive range of products, each crafted to meet stringent quality standards and reflect their commitment to excellence and innovation.
- Revenue: Not publicly disclosed
- Founded: 2004
- Location: Vista, CA, USA
- Certifications: GMP-compliant, FDA-registered facility
- Specialties: Turnkey contract manufacturing for vitamins/supplements (capsules, tablets, powders, liquids), R&D, packaging
- Production Capacity: Supports small to large production runs
- Compliance: Operates to FDA cGMP 21 CFR 111
They stand out for their hands-on customer service, providing detailed guidance through every stage of the manufacturing process, from formulation to final packaging.
Aegle Nutrition
Aegle Nutrition provides a diverse portfolio of contract services, ensuring every product meets high standards of quality and performance.
- Revenue: Not publicly disclosed
- Founded: 2013
- Location: Carrollton, TX, USA
- Certifications: cGMP-compliant, FDA-registered facility
- Specialties: Private label & contract manufacturing—capsules, liquids/beverages, powders, cosmetics/skin care; formulation to fulfillment
- Production Capacity: Flexible runs across multiple dosage forms
- Compliance: Operates to FDA cGMP standards
What sets them apart is their ability to handle multi-format product lines, allowing brands to consolidate all their manufacturing needs under one roof.
Pharma Natural
Pharma Natural specializes in vitamins and supplements crafted to support overall health and wellness, maintaining a strong focus on quality control.
- Revenue: Not publicly disclosed
- Founded: 2002
- Location: Miami Lakes, FL, USA
- Certifications: FDA-registered, cGMP-compliant facility
- Specialties: Custom/private-label vitamins & nutraceuticals; liquids, capsules, tablets; in-house R&D and packaging
- Production Capacity: 48,000 sq ft facility supporting a wide range of SKUs
- Compliance: FDA-registered, operates under cGMP standards
Their strength lies in offering flexible production volumes, making them equally suited to serve emerging brands and high-volume national retailers.
Gummi World
Established in 2020, they have carved a niche in the market with a variety of flavors and nutritional profiles, all produced to high standards of quality and efficacy.
- Revenue: Not publicly disclosed (some reports claim ~$250M, unverified)
- Founded: 2019
- Location: Chandler, AZ, USA
- Certifications: FDA-registered, cGMP-compliant, OTC-certified
- Specialties: Custom gummy vitamins, softgels, and capsules; R&D, packaging, fulfillment
- Production Capacity: Small-batch to large-scale gummy production
- Compliance: Operates under cGMP with OTC certification
They’re recognized for their collaborative R&D lab, where clients can work directly with food scientists to create unique, marketable gummy products.
Makers Nutrition
Makers Nutrition focuses on delivering high-quality nutraceuticals, ensuring every product reflects their commitment to excellence.
- Revenue: Estimate: $50–99.9M
- Founded: 2014
- Location: Commack/Hauppauge, NY, USA
- Certifications: NSF/ANSI 455-2 GMP, FDA-registered facility
- Specialties: Private-label & contract manufacturing; formulation, packaging, labeling, warehousing, fulfillment
- Production Capacity: MOQs as low as 500 units on stock formulas; larger runs for custom programs
- Compliance: Third-party NSF GMP audits and FDA registration
Their extensive network of suppliers and logistics partners allows them to secure premium ingredients and offer streamlined fulfillment options for growing e-commerce brands.
FoodScience LLC
FoodScience has a longstanding tradition of manufacturing vitamins and supplements. Their decades of experience ensure that every product is produced to meet the highest standards of quality and efficacy.
- Revenue: Estimate: $26.8M
- Founded: 1973
- Location: Williston, VT, USA
- Certifications: SQF-certified, cGMP-compliant, FDA-registered facility
- Specialties: Manufacturing of vitamins and supplements for human & pet brands; in-house brands include DaVinci Laboratories and Pet Naturals
- Production Capacity: Full-service manufacturing with multiple dosage forms
Compliance: Operates to SQF and cGMP standards
They’re also one of the few manufacturers with a strong in-house brand portfolio, giving them real-world insight into what it takes to succeed in today’s competitive supplement market.
NutraScience Labs
NutraScience has been a reliable name in the custom manufacturing of nutritional and dietary supplements since 2015.
- Revenue: Estimate - $24M
- Founded: 2015
- Location: Farmingdale, NY, USA
- Certifications: cGMP-compliant, FDA-registered facility
- Specialties: Custom formulation, powder blending, capsules, tablets, packaging, labeling, and fulfillment services
- Production Capacity: Scalable manufacturing for small to large orders across multiple dosage forms
- Compliance: Operates under FDA cGMP (21 CFR 111) with regular third-party quality audits
Their services, including powder blending and formulation, reflect a strong dedication to quality and client satisfaction. They’re valued for their transparent project management, keeping clients informed and ensuring smooth, timely product launches.
Leveraging Partners for Seamless Business Growth
Many brands working with the supplement manufacturers have to choose to launch private-label supplements.
In this setup, the manufacturer produces ready-made formulas, while a separate platform or a supplement fulfillment partner like Supliful can handle storage, packaging, and shipping.
This approach allows businesses to benefit from the manufacturer’s established quality processes while streamlining logistics through third-party services. It’s a practical way to get to market faster without having to manage every stage of production in-house.
Some of the best private label supplement manufacturers stand out for offering both flexibility in product selection and transparent quality control documentation.
By understanding how these manufacturers operate, you can build a reliable supply chain that balances speed, quality, and scalability.
Choosing a Supplement Manufacturer in the USA: Things You Must Consider Before Picking Your Partner
Selecting the right manufacturing partner can make or break your supplement business. The USA's top supplement manufacturers share common qualities, experience, compliance, and a dedication to product quality that sets them apart. Here’s what to consider:
Proven Experience and Reliability
Working with an experienced manufacturer reduces the risk of costly mistakes and ensures your products meet industry standards from day one.
- Years the company has been in operation
- Track record of delivering high-quality products
- Transparency in production processes
Compliance with GMP Standards
Good Manufacturing Practices (GMPs) ensure supplements are produced safely and consistently. A manufacturer committed to GMP compliance safeguards your brand’s reputation.
- Verified GMP certification
- Regular audits and inspections
- Documented safety and quality procedures
Competitive Pricing and Efficient Production
Balancing cost with production efficiency is key to staying competitive without compromising quality.
- Transparent pricing structure
- Quick turnaround times
- Ability to scale production as your business grows
Custom Formulation and Design Support
If your business model depends on unique product offerings, choose a manufacturer that supports customization and branding.
Regulatory Compliance and Transparency
Manufacturers should be fully compliant with U.S. regulations and open about their sourcing and production standards.
- FDA registration and relevant licenses
- Ingredient sourcing transparency
- Accessible quality control documentation
Collaborative Partnership
A responsive and adaptable manufacturer can grow alongside your business, adjusting to market demands and your evolving needs.
- Willingness to accommodate special requirements
- Clear communication channels
- Consistent, dependable customer support
Moving Forward with the Proven Manufacturer on Your Side
Finding the right manufacturing partner is a decision that shapes your brand’s future. By focusing on quality, flexibility, and a shared commitment to excellence, you can build a product line that stands out in the market and earns lasting customer trust.
Take the time to evaluate your options, ask the right questions, and choose a partner who can grow alongside your business. The right collaboration today can set the foundation for years of success.
FAQ
The top US private label supplement makers include Supplement Manufacturing Partner Inc. with a revenue over $250 million, Gummi World with a revenue over $250 million, and Aegle Nutrition with a revenue over $250 million. These companies are renowned for their quality and innovation in the supplement manufacturing industry.
When choosing a private label supplement partner, it's crucial to consider their manufacturing capabilities, quality assurance, industry experience, and customer service. Transparency, reliability, and adherence to regulatory standards are also key factors.
Manufacturers such as Vitakem, NutraCap Labs, and Private Label Supplements have a strong focus on producing organic or non-GMO supplements, ensuring products are natural and free from genetically modified organisms.
Successful partnerships with top supplement manufacturers stem from clear communication, aligned goals, and mutual understanding. Ensure that the manufacturer understands your product vision, quality expectations, and market objectives.
The delivery speed for large orders varies among manufacturers. Companies like NutraCap Labs and Makers Nutrition are known for their efficient production processes and timely delivery of large orders.
Yes, most top manufacturers have a minimum order size requirement. This varies from company to company, and it's essential to discuss and understand these requirements upfront.
Top manufacturers guarantee product quality and safety through stringent quality control measures, adherence to Good Manufacturing Practices (GMPs), and thorough testing of products for purity, potency, and safety.
How cost-effective are the top manufacturers for private label needs?
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